Table 2. HAMD17 and HAMA Scores at Baseline and Endpoint.
| MEAN ± SD (MIN; MAX) TOTAL = 1466 | CGI-S (0;7) | HAMD17 TOTAL (0;52) | HAMD17 ANXIETY/SOMATISATION (ITEMS 10-13, 15, 17) (0;18) | HAMA TOTAL 14 ITEMS (0;56) | HAMA SOMATIC ANXIETY (ITEMS 1-6, 14) (0;28) | HAMA PSYCHIC ANXIETY (ITEMS 7-13) (0;28) |
|---|---|---|---|---|---|---|
| Baseline | 4.4 ± 0.6 (3;7) | 21.9 ± 3.7 (14;37) F 22.1 ± 3.7 M 21.5 ± 3.7 | 7.2 ± 2.0 (1;14) F 7.3 ± 1.9 M 7.0 ± 2.0 | 18.6 ± 5.7 (3;41) F 19.2 ± 5.8 M 17.4 ± 5.3 | 11.4 ± 2.9 (2;24) F 11.6 ± 2.9 M 11.0 ± 2.9 | 7.2 ± 3.7 (0;23) F 7.6 ± 3.8 M 6.4 ± 3.3 |
| Endpoint | 2.8 ± 1.3 (1;7) | 11.4 ± 7.1 (0;40) F 11.5 ± 7.2 M 11.3 ± 6.9 | 4.2 ± 2.6 (0;15) F 4.3 ± 2.6 M 4.1 ± 2.6 | 10.5 ± 6.8 (0;50) F 10.7 ± 7.1 M 10.1 ± 6.4 | 6.2 ± 4.2 (0;27) F 6.2 ± 4.3 M 6.1 ± 4.0 | 4.3 ± 3.4 (0;23) F 4.5 ± 3.5 M 4.0 ± 3.1 |
| Change from baseline to endpoint | −10.5 ± 7.1 (−32;21) F −10.6 ± 7.1 M −10.2 ± 7.2 | −3.0 ± 2.9 (−12;11) F −3.0 ± 2.8 M −2.8 ± 3.0 | −8.0 ± 7.1 (−31;15) F −8.4 ± 7.2 M −7.2 ± 6.7 | −5.2 ± 4.3 (−17;9) F −5.3 ± 4.3 M −4.9 ± 4.1 | −2.9 ± 3.7 (−15;11) F −3.1 ± 3.8 M −2.4 ± 3.4 |
CGI-S, Clinical Global Impression-Severity scale; F, female; HAMA, Hamilton Anxiety scale; HAMD17, 17-item Hamilton Depression Rating scale; M, male; SD, standard deviation.