Table 6. Concurrent Validity of the Newly Identified HAMD₁₇ Factors 1 to 4 (Spearman’s Coefficient).

CORRELATION	BASELINE	WEEK 1	W 2	W 3	W 5	W 7	W 9	ENDPOINT
HAMD17 factor 1 (items 4, 5, 6) Sleep
With:
CGI-S (mean score)	0.21	0.28	0.31	0.4	0.42	0.44	0.41	0.48
HAMD17 factor 2 (items 2, 3, 17) Severity
With:
CGI-S (mean score)	0.16	0.27	0.38	0.47	0.49	0.47	0.46	0.6
HAMD17 factor 3 (items 1, 7, 8) Core symptoms
With:
CGI-S (mean score)	0.26	0.46	0.61	0.71	0.74	0.77	0.79	0.84
HAMD17 factor 4 (items 10, 11, 15) Anxiety/hypochondriasis
With:
HAMD anxiety/somatisation (6 items)	0.9	0.89	0.9	0.92	0.92	0.91	0.91	0.93
HAMA total	0.46	0.54	0.6	0.66	0.71	0.71	0.7	0.77
HAMA somatic anxiety	0.34	0.45	0.51	0.58	0.65	0.66	0.65	0.71
HAMA psychological anxiety	0.44	0.49	0.53	0.6	0.6	0.61	0.59	0.66
CGI-S (mean score)	0.25	0.35	0.44	0.5	0.56	0.56	0.58	0.63

CGI-S, Clinical Global Impression-Severity scale; HAMA, Hamilton Anxiety scale; HAMD₁₇, 17-item Hamilton Depression Rating scale.