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. 2016 Sep 30;9:91. doi: 10.3389/fnmol.2016.00091

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Copyright © 2016 Thiere, Kliche, Müller, Teuber, Nold and Stork.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Association of ADAP with MAP2-positive structures in hippocampal neurons. (A) Confocal microscopy reveals that during early neurite formation (DIV3), ADAP is richly expressed along outgrowing neurites and highly co-localized with MAP2. Co-localization is evident in both the core neurite and at the growth tip, including filamentous and filopodial structures. Only occasionally, small MAP2-negative filaments appear labeled by ADAP (arrows). Scale bars, 100 μm and 50 μm. (B) A high degree of co-localization with MAP2 is also evident at later stages of dendrite development (DIV10). Scale bar, 100 μm.