FIG 2.

Ex vivo HIV coreceptor (CCR5) expression on CD25⁺ Foxp3⁺ CD4 T cells. (A) A histogram overlay of CCR5 expression on total CD4 T cells (gray) and CD25⁺ Foxp3⁺ CD4 T cells (black). (B) The frequencies of CCR5-expressing CD25⁺ Foxp3⁺ CD4 T cells are compared between HIV-negative and -positive subjects. For maximum staining sensitivity, fresh anticoagulated whole blood of individuals from the WHIS cohort was used to determine CCR5 expression on CD4 T cells. Statistical analysis was performed using the Mann-Whitney test.