TABLE 2.
Subject ID | HIV infection duration (mo) | % of cell-derived sequences quasi-identical to plasma-derived sequences (n) | Mean no. of nt substitutions between plasma and cell-derived sequences | Cellular origin of closest sequence | No. of nt substitutions | Cellular origin of most distant sequence | No. of nt substitutions |
---|---|---|---|---|---|---|---|
H574 | 9–12 | 11.4 (8 of 70) | 6 | CD25+ FoxP3+ Helios− | 1 | CD25+ FoxP3+ Helios+ | 16 |
CD25+ FoxP3+ Helios+ | 1 | ||||||
CD25− FoxP3− Helios+ | 1 | ||||||
CD25− FoxP3− Helios− | 1 | ||||||
H605 | 27–30 | 6.8 (3 of 44) | 39 | CD25− Foxp3− Helios− | 3 | CD25+ FoxP3+ Helios+ | 32 |
6233K12 | 16–38 | 1.9 (1 of 53) | 30 | CD25− FoxP3− Helios+ | 2 | CD25− FoxP3− Helios+ | 30 |
9440A11a | >38 | 2.6 (1 of 38) | 46 | CD25+ Helios+ | 4 | CD25+ Helios+ | 76 |
8710U11 | >38 | 0 (0 of 39) | 57 | CD25− FoxP3− Helios− | 32 | CD25− FoxP3− Helios− | 67 |
8975T11 | >54 | 0 (0 of 55) | 53 | CD25− FoxP3− Helios+ | 54 | CD25− FoxP3− Helios− | 86 |
Cells (PBMCs) from this subject were sorted into four populations only on the basis of CD25 and Helios expression on memory (CD45RO) CD4 T cells.