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. 2016 Sep 29;90(20):9495–9508. doi: 10.1128/JVI.01107-16

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FIG 2 — SM111 has minimal toxicity in comparison to that of reported acylguanidine compounds. (A to C) Effects of SM111 (blue), SM113 (green), HMA (purple), and BIT-225 (red) on viability of uninfected CEM-GXR cells (A) and cellular ATP in uninfected (B) and infected (C) CEM-GXR cells after 6 days. (D to F) Effects of compounds on viability of uninfected PBMC (D) and cellular ATP in uninfected (E) and infected (F) PBMC after 6 days. For panels A, B, D, and E, data are representative of three independent experiments performed in triplicate. For panels C and F, histograms and error bars represent means ± standard deviations (SD) calculated from three independent experiments (C) and using cells from three different donors (F), performed in triplicate.