TABLE 2.

Gene ontology enrichment analysis using mean log P value for biological process terms

Total no. of genes in set	No. of tested genes in seta	Gene set statisticb	Gene set P valuec	Gene set description
156	100	1.903920114	1.46E−28	Xenobiotic metabolic process
137	99	1.620075009	2.68E−12	Response to nutrient
41	24	2.680057789	1.21E−11	Secondary metabolic process
14	10	3.896239669	1.23E−10	Glycoside metabolic process
91	55	1.879901718	1.95E−10	Terpenoid metabolic process
8	6	5.132219556	3.30E−10	Aminoglycoside antibiotic metabolic process
8	6	5.132219556	3.30E−10	Daunorubicin metabolic process
8	6	5.132219556	3.30E−10	Doxorubicin metabolic process
80	48	1.962377737	4.01E−10	Diterpenoid metabolic process
110	69	1.72724906	4.74E−10	Isoprenoid metabolic process
60	42	2.044646234	6.84E−10	Tetrapyrrole metabolic process
9	7	4.598087516	7.69E−10	Polyketide metabolic process
12	7	4.582972329	8.76E−10	Flavonoid metabolic process
39	28	2.353678461	1.09E−09	Porphyrin-containing compound metabolic process
101	68	1.701032533	2.89E−09	Unsaturated fatty acid metabolic process
88	60	1.758042245	4.39E−09	Icosanoid metabolic process
88	60	1.758042245	4.39E−09	Fatty acid derivative metabolic process
76	46	1.912375696	8.92E−09	Retinoid metabolic process
94	67	1.668312943	2.07E−08	Cellular hormone metabolic process
10	9	3.494980169	1.01E−07	Xenobiotic catabolic process
35	22	2.346522543	1.86E−07	Drug metabolic process
21	14	2.747511772	3.61E−07	Retinoic acid metabolic process
23	17	2.498626389	7.22E−07	Quinone metabolic process
9	6	3.99034837	9.37E−07	Omega-hydroxylase P450 pathway
6	5	4.310759589	1.04E−06	Porphyrin-containing compound catabolic process
6	5	4.310759589	1.04E−06	Tetrapyrrole catabolic process
6	5	4.310759589	1.04E−06	Heme catabolic process
6	5	4.310759589	1.04E−06	Pigment catabolic process
67	46	1.756731978	1.40E−06	Regulation of smooth muscle cell proliferation

^aTested genes are those in the gene set for which a gene statistic has been submitted.

^bMean −log10 value of the tested genes in the gene set.

^cP value corresponding to the gene set statistic.