TABLE 2.
Dynamic light scattering measurements of SOSIP.v1 trimer dimensions, purity, and thermal stability
| Env | Hydrodynamic radius (nm) | Polydispersity (%) | Molecular mass (kDa)a | Temp for onset of melting (°C) |
|---|---|---|---|---|
| BG505.c2 | 6.7 | 5.0 | 284.5 | 64.0 |
| PVO.4 | 6.6 | 6.2 | 281.6 | 60.3 (3 mg/ml) |
| BF520.e3 | 6.7 | 4.3 | 292.8 | 63.3 |
| BS208.b1 | 6.5 | 3.4 | 268.1 | 68.4 (temp for onset of aggregation, 84.7) |
| KNH1144 | 6.7 | 4.7 | 287.0 | 62.6 |
| KNH1144 A162T | 6.8 | 3.9 | 300.0 | 65.8 |
| MG505.e1 | 6.8 | 2.7 | 301.95 | 65.3 |
a
Molar mass derived from DLS estimates of size, density, and particle conformation.