Table 1.

Classes of antiretrovirals with their respective Food Drug and Administration (FDA) market-approved year

Antiretrovirals before 1998	Antiretrovirals since 1998
NRTI	NRTI
ddi (1991)	Abacavir (1998)
ddC (1992)
d4T (1994)
Lamivudine (1995)
Zidovudine (1987)
Combivir (1997)
NNRTI	NNRTI
Delavirdine (1997)	Efavirnez (1998)
Nevirapine (1997)
Protease inhibitor	Protease inhibitor
Saquinavir (1995)	Amprenavir (1999)
Ritonavir (1996)	Lopinavir/Ritonavir (2000)
Nelfinavir (1997)
Indinavir (1996)

NRTI, nucleoside reverse transcriptase inhibitors; NNRTI, non-nucleoside reverse transcriptase inhibitors.