Table 1.

In vitro biocompatibility and hemocompatibility of Mg alloys used for stent applications

Alloy	Cell type	Viability	Hemocompatibility	Culture time (day)	Authors and references
MgCa 0.4%	HUVEC; HUVSMC	<5%; ~90%	–	10	Drynda et al.[6]
MgCa 0.6%		<5%; ~80%
MgCa 0.8%		<5%; ~90%
MgCa 1.2%		<5%; ~70%
MgCa 2.0%		<5%; ~70%
Mg–Nd–Zn–Zr	HUVEC cell line EA.hy926	10% Extract: ~95%	Hemolysis ratio: 52%	1	Mao et al.[7]
		50% Extract: ~85%
		10% Extract: ~110%		3
		50% Extract: ~110%
		10% Extract: ~ 15%		5
		50% Extract: ~120%
Mg3.5Li	HUVEC cell line ECV304; rodent VSMC	~85%; ~135%	Hemolysis ratio: ~3.8%	1	Zhou et al.[8]
		~90%; ~80%	Adhered platelets: ~9000	3
		~87%; ~80%		5
Mg8.5Li	HUVEC cell line ECV304; rodent VSMC	~95%; ~200%	Hemolysis ratio: ~3%	1	Zhou et al.[8]
		~80%; ~110%	Adhered platelets: ~9000	3
		~80%; ~105%		5
Mg8.5Li1Al	HUVEC cell line ECV304; rodent VSMC	~93%; ~198%	Hemolysis ratio: ~4%	1	Zhou et al.[8]
		~75%; ~100%	Adhered platelets: ~5000	3
		~90%; ~90%		5
Mg3.5Li2Al2RE	HUVEC cell line ECV304; rodent VSMC	~80%; ~125%	Hemolysis ratio: ~4.2%	1	Zhou et al.[8]
		~80%; ~75%	Adhered platelets: ~5000	3
		~90%; ~70%		5
Mg3.5Li4Al2RE	HUVEC cell line ECV304; rodent VSMC	~80%; ~125%	Hemolysis ratio: ~4.2%	1	Zhou et al.[8]
		~80%; ~90%	Adhered platelets: ~13 000	3
		~70%; ~90%		5
Mg8.5Li2Al2RE	HUVEC cell line ECV304; rodent VSMC	~40%; ~105%	Hemolysis ratio:~7.5%	1	Zhou et al.[8]
		~75%; ~75%	Adhered platelets: ~3000	3
		~70%; ~70%		5
WE42	HUVEC	~75%	–	1	Guo et al.[9]
Mg–0.5Sr	HUVEC	~98%	–	1	Bornapour et al.[10]
		~102%		4
		~112%		7
WE43	HUVEC	~104%	–	1	Bornapour et al.[10]
		~110%		4
		~104%		7
Mg–2.5Nd–0.2Zn–0.4Zr	HUVEC	10% Extract: ~95%	–	1	Mao et al.[11]
		50% Extract: ~90%
		10% Extract: ~110%		3
		50% Extract: ~110%
		10% Extract: ~110%		5
		50% Extract: ~120%

Note: HUVEC = human umbilical endothelial cell.