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Plots of observed glucose concentrations (open circles), population model predictions (dotted line), and individual model predictions (solid line) from the dose–fasting glucose concentration PKPD model for glucose response to glibenclamide.
Notes: Each cell represents the data for an individual subject shown as a dose–response plot, ie, y-axis shows fasting glucose concentration in mmol/L and x-axis shows dose in mg.
Abbreviation: PKPD, pharmacokinetic/pharmacodynamic.
