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. 2016 Sep 26;8:141–153. doi: 10.2147/CPAA.S102674

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© 2016 Rambiritch et al. This work is published and licensed by Dove Medical Press Limited

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Plots of observed glucose concentrations (open circles), population model predictions (dotted line), and individual model predictions (solid line) for the steady state concentration (Cpss)-mean glucose concentration PKPD model for glucose response to glibenclamide.

Notes: Each cell represents the data for an individual subject shown as a dose–response plot, ie, y-axis shows fasting glucose concentration in mmol/L and x-axis shows dose in mg.

Abbreviation: PKPD, pharmacokinetic/pharmacodynamic.