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. 2014 Dec 5;2:197–213. doi: 10.2147/HP.S47598

Figure 4.

Figure 4

Integrated physiological functions associated with HIF hydroxylase pathways.

Notes: In addition to effects on physiological systems classically associated with the maintenance of oxygen homeostasis, studies of the hypoxia-inducible factor (HIF) hydroxylase system have revealed actions on many other processes which are not classically associated with physiological adaptation to hypoxia and potentially widen the role of hypoxia in integrated physiology.