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. 2015 Oct 8;3:45–52. doi: 10.2147/HP.S90555

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© 2015 Lelli et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License.

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Oxygen-dependent regulation of the lncRNAs NEAT1 and MALAT1 in vivo.

Notes: Groups of three mice were exposed to an inspiratory O₂ concentration of 8% for 0, 4, 24, and 108 hours as indicated. Whole organ lncRNA levels were determined by RT-qPCR and displayed as ratio to the β-actin constitutive control mRNA levels in Log2 scale.

Abbreviations: h, hours; lncRNAs, long noncoding RNAs; mRNA, messenger RNA; NEAT1, nuclear-enriched abundant/autosomal transcript 1; MALAT1, metastasis-associated lung adenocarcinoma transcript 1; RT-qPCR, quantitative reverse transcription polymerase chain reaction.