Table 3. Sensitivity analysis results for chronotropic dromotropic and inotropic responses.

Main, total and interaction effects are expressed as percentage, along with their corresponding 95% confidence intervals [c.i. 95%], computed using a bootstrap approach.

Chronotropic	Main (%)	Total (%)	Interactions (%)
Pcur	47.45 (± 8.83)	71.79 (± 5.52)	24.34 (± 9.35)
	[41.50, 54.01]	[68.11, 76.15]	[17.89, 30.93]
Pnpulses	6.37 (± 2.58)	14.23 (± 4.62)	7.86 (± 3.56)
	[4.16, 7.97]	[11.01, 17.68]	[4.98, 10.41]
Ppw	18.60 (± 2.97)	38.01 (± 11.21)	19.42 (± 10.36)
	[15.96, 20.41]	[29.79, 46.12]	[12.85, 27.58]
Pipp	0.21 (± 0.16)	0.64 (± 0.41)	0.43 (± 0.25)
	[0.10, 0.34]	[0.38, 0.99]	[0.27, 0.64]
Pdel	0.88 (± 1.47)	2.26 (± 3.36)	1.34 (± 1.9)
	[0.22, 2.68]	[0.70, 6.42]	[0.48, 3.69]
Dromotropic	Main (%)	Total (%)	Interactions (%)
Pcur	48.26 (± 11.71)	68.31 (± 11.67)	20.05 (± 3.75)
	[42.74, 62.44]	[61.97, 79.62]	[17.08, 22.53]
Pnpulses	6.16 (± 5.34)	13.71 (± 8.00)	7.55 (± 4.17)
	[3.01, 10.94]	[6.95, 18.70]	[4.03, 10.17]
Ppw	21.21 (± 8.78)	39.87 (± 8.96)	18.66 (± 5.93)
	[14.75, 27.44]	[33.39, 46.43]	[15.49, 24.70]
Pipp	0.13 (± 0.09)	2.85 (± 5.74)	2.71 (± 5.6)
	[0.04, 0.19]	[0.44, 9.91]	[0.35, 9.72]
Pdel	0.61 (± 0.67)	2.86 (± 2.83)	2.24 (± 2.51)
	[0.19, 1.17]	[1.11, 5.26]	[0.61, 4.53]
Inotropic	Main (%)	Total (%)	Interactions (%)
Pcur	52.82 ± 15.36	68.70 ± 12.45	15.87 ± 6.61
	[39.60, 62.34]	[56.97, 76.55]	[11.66, 21.43]
Pnpulses	5.19 ± 4.13	12.43 ± 9.48	7.23 ± 6.25
	[2.53, 8.57]	[5.57, 19.29]	[3.12, 12.10]
Ppw	22.94 ± 5.93	35.92 ± 11.40	12.97 ± 6.18
	[18.93, 27.65]	[29.21, 46.83]	[9.55, 19.02]
Pipp	0.37 ± 0.46	1.48 ± 1.52	1.11 ± 1.26
	[0.10, 0.83]	[0.676, 3.120]	[0.49, 2.63]
Pdel	0.96 ± 1.13	2.51 ± 1.84	1.54 ± 1.29
	[0.28, 2.01]	[1.05, 3.71]	[0.76, 2.71]