Table 3.

Amplitudes and latencies of the P300 and MMN components

	Control (n=10)		Baseline (n=14)		After 1 year of treatment (n=14)		Control vs baselinea		Baseline vs 1 year of treatment b
	Mean	SE	Mean	SE	Mean	SE	t-value	P-value	t-value	P-value
P300 amplitude (µV)
Fz	−14.74	1.57	−10.53	1.69	−15.26	2.57	1.33	0.10	2.58	<0.05
Cz	−16.52	1.06	−12.41	1.10	−16.72	1.75	2.25	<0.05	2.43	<0.05
Pz	−18.52	1.37	−14.59	1.25	−17.34	1.62	1.71	0.05	1.44	0.17
C3	−13.27	1.23	−10.66	1.24	−14.13	1.51	0.99	0.17	2.20	<0.05
C4	−14.93	1.47	−11.38	0.96	−16.19	1.77	1.77	<0.05	2.29	<0.05
P300 latency (ms)
Fz	312.60	11.48	316.80	4.43	332.15	7.74	0.53	0.70	1.40	0.19
Cz	310.40	10.55	317.07	4.72	333.39	7.56	0.06	0.52	1.49	0.16
Pz	312.40	10.93	321.33	4.18	332.77	7.61	0.28	0.39	0.91	0.38
C3	316.30	11.70	319.40	5.02	333.31	6.95	0.81	0.79	1.50	0.16
C4	315.50	11.75	320.33	5.25	333.77	7.70	0.47	0.68	1.21	0.25
MMN amplitude (µV)
Fz	5.59	1.52	5.56	1.06	6.65	1.67	2.36	0.99	0.96	0.36
Cz	4.59	1.12	5.42	0.86	5.49	1.21	0.15	0.56	0.39	0.70
Pz	2.48	0.87	4.06	0.68	3.42	0.99	1.02	0.16	0.19	0.85
C3	3.73	1.11	5.48	0.73	4.83	0.92	0.94	0.18	0.27	0.79
C4	3.33	0.99	5.53	0.98	4.47	0.96	1.08	0.14	0.54	0.60
MMN latency (ms)
Fz	121.08	10.61	122.44	6.01	122.83	6.54	1.35	0.91	0.47	0.96
Cz	122.30	10.69	121.95	6.05	123.04	6.62	2.08	0.98	0.10	0.92
Pz	119.28	9.86	122.08	5.96	122.49	7.19	0.85	0.80	0.04	0.97
C3	120.66	10.82	122.31	6.20	122.71	7.27	1.25	0.89	0.04	0.97
C4	120.86	10.40	122.09	5.84	122.83	7.05	1.40	0.91	0.04	0.97

Notes:

^aStudent’s t-tests were used.

^bPaired t-tests were used (with Bonferroni–Holm adjusted P-values).

Abbreviations: MMN, mismatch negativity; SE, standard error.