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IPA analyses of differential proteins from low- to high-grade astrocytomas.
Notes: Disease and function analysis (A) and canonical pathways (B) in grade II, III, and IV astrocytomas. Z-score >2: significantly activated; Z-score <−2, significantly inhibited. −Log (P-value) >1.5: significantly enriched.
Abbreviations: eIF2, eukaryotic initiation factor 2; IPA, ingenuity pathway analysis; mTOR, mechanistic target of rapamycin; Wnt, Wingless and int 1.
