Table 2.

Quantitative value of candidate biomarkers by iTRAQ and Western blot quantitation methods

Protein name	Accession number	iTRAQ quantification	Western blot
EGFR	E9PFD7	1:3.7:2.2:2.5	1:1.64:1.86:1.89
TIMP1	P01033	1:1.1:1.1:2.3	1:1.09:1.32:1.80
MMP9	P14780	1:1.5:1.5:8.3	1:1.80:1.51:2.00
FBLN5	G3V4U0	1:0.5:0.4:0.6	1:0.76:0.53:0.36
FBLN2	F5H1F3	1:0.4:0.1:0.2	1:0.40:0.23:0.14

Abbreviations: EGFR, epidermal growth factor receptor (OS = Homo sapiens GN = EGFR; PE =3 SV =2); FBLN2, fibulin-2 (OS = Homo sapiens GN = FBLN2 PE =4 SV =1); FBLN5, fibulin-5 (OS = Homo sapiens GN = FBLN5 PE =4 SV =1); iTRAQ, isobaric tags for relative and absolute quantitation; MMP9, matrix metalloproteinase-9 (OS = Homo sapiens GN = MMP9 PE =1 SV =3); TIMP1, metalloproteinase inhibitor 1 (OS = Homo sapiens GN = TIMP1 PE =1 SV =1).