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. Author manuscript; available in PMC: 2016 Sep 30.
Published in final edited form as: J Hepatol. 2015 Jan 29;62(6):1272–1277. doi: 10.1016/j.jhep.2015.01.021

Fig. 1. The effect of CB1 antagonist, AM251, on cardiac contractility.

Fig. 1

(A) Left ventricular pressure-volume loop. AM251 (3 mg kg−1) treatment increased end-systolic ventricular pressure and reduced end-diastolic volume in BDL animals but did not have a significant effect in sham control rats (n = 3). (B) AM251 treatment significantly increased ESPVR in the BDL group while it had no significant effect in sham control animals (n = 3). ESPVR: end-systolic pressure-volume relationship.