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. 2016 Aug 31;8(8):e761. doi: 10.7759/cureus.761

Table 2. Published Case Reports of Radiotherapy for the Treatment of Chylothorax Secondary to Malignancy.

CLL = chronic lymphocytic leukemia; HL = Hodgkin's lymphoma; HN = head and neck; LN = lymph node; NHL = non-Hodgkin's lymphoma

Study Age (sex) Diagnosis Effusion Radiotherapy Dose            (# = fractions) Outcome
Ampil [11] 74 F CLL Left 1,000 cGy in 5# to the mediastinum Resolved at 6 weeks
Cigarral [12] 58 M Metastatic prostate cancer pelvic LN, retroperitoneum, mediastinum, HN Bilateral 3,000 cGy in 10# Patient condition deteriorated and radiation was not completed
Daly [13] 42 M Stage IV NHL, mediastinal mass Left 3,000 cGy in 10# Resolution after 6 fractions. No re-accumulation at 3 months.
Gerstein [10] 45 F Stage IVA follicular lymphoma, celiac trunk Bilateral Right > Left 1,500 cGy in 10# with a boost of 540 cGy in 3# Improvement after 5 fractions; resolution at the end of radiotherapy. No re-accumulation at 16 months.
Heaton [14] 70 F Anaplastic carcinoma, mediastinum Right 4,000 cGy Resolution at the end of radiotherapy.  No re-accumulation at 2.5 years.
Janjetovic [15] 28 M Stage IIA HL, mediastinal mass Left 3,000 cGy Significant regression at the end of radiotherapy.
Little [16] 66 M Metastatic prostate cancer, lungs, supraclavicular LN Left 4,400 cGy to the mediastinum and left supraclavicular LN Resolved and controlled at 5 months.
Scholz [17] 65 M CLL Right 2,400 cGy to the mediastinum and thoracic duct Persisted at 8 weeks.
Swenson [18] 28 M Lymphosarcoma, abdomen Bilateral 3,150 rads in 25# Resolution at the end of radiotherapy
48 M Lymphosarcoma, abdomen   Left 3,850 rads in 25# Resolution mid-way through radiotherapy. No re-accumulation at 3 months
Tan [19] 53 M Stage IV NHL with concurrent tuberculosis Bilateral Mediastinal radiation Persisted for 57 days
Van De Voorde [20] 63 F Stage IIE follicular lymphoma, celiac trunk Right 400 cGy in 2# Resolution at the end of radiotherapy. No re-accumulation at 6 months
Zimhony [21] 81 F CLL Left 2,100 cGy to the mediastinum Persisted