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. 2016 Apr 11;7(20):29131–29142. doi: 10.18632/oncotarget.8675

Figure 4. Effect of A674563 on FLT3-ITD-positive primary AML patient cells and in vivo anti-tumor activity.

Figure 4

(A) Anti-proliferative effect of A674563 on FLT3-ITD-positive AML patient primary cells and normal bone marrow cells. (B) Effect of A674563 on MOLM14 xenograft model. (C) Tumor size demonstration by visual measurement. (D) Immunohistochemistry staining (HE, Ki-67 and TUNNEL) of tumor tissues.