Table 2. A674563 anti-proliferative effects against FLT3 wt/mutant transformed BaF3 isogenic cell lines.
Cell lines | A674563 (GI50: μM) |
---|---|
BaF3-TEL-FLT3-wt | 1 |
BaF3-FLT3-ITD | 0.088 |
BaF3-FLT3-D835Y | 0.075 |
BaF3-FLT3-ITD-D835Y | 0.42 |
BaF3-FLT3-ITD-F691L | 0.43 |
BaF3 | 1.6 |