Table 4. Meta-regression with the covariates.

Covariates	All EGFR mutations					Exon 19 deletion					L858R point mutation
	Coefficient	Standard error	P value	RDOR	95% CI	Coefficient	Standard error	P value	RDOR	95% CI	Coefficient	Standard error	P value	RDOR	95% CI
Country	0.005	0.2880	0.9852	1.01	0.55-1.85	0.151	0.6364	0.8217	1.16	0.23 – 5.97	0.376	0.4240	0.4158	1.46	0.49 - 4.33
Bloos type	0.182	0.8601	0.8354	1.2	0.19-7.43	−1.387	1.2545	0.3191	0.25	0.01 – 6.28	−1.297	0.9576	0.2335	0.27	0.02 – 3.20
Size	−0.753	0.7923	0.3560	0.47	0.09-2.53	−0.918	1.2378	0.4915	0.40	0.02 – 9.62	0.912	0.9504	0.3811	2.49	0.22 – 28.66
Method	0.011	0.1443	0.9414	1.01	0.74-1.37	0.268	0.4298	0.5592	1.31	0.43 – 3.95	0.232	0.3021	0.4774	1.26	0.58 – 2.74

EGFR: epidermal growth factor receptor; 95 % CI: 95 % confidence interval; RDOR: relative diagnostic odds ratios