Table 3. Multivariate Cox regression analysis of prognostic factors influencing the survival of patients with lymph node-positive cervical cancer.
| Variable | CCSS | OS | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | |
| Year of diagnosis (continuous variable) | 0.963 | 0.948–0.977 | < 0.001 | 0.967 | 0.954–0.979 | < 0.001 |
| Age (categorical variable) | 1.148 | 0.957–1.376 | 0.136 | 1.161 | 1.399–1.866 | < 0.001 |
| Tumor histology | 1.393 | 1.252–1.551 | < 0.001 | 1.340 | 1.225–1.467 | < 0.001 |
| FIGO stage | 1.748 | 1.467–2.083 | < 0.001 | 1.657 | 1.430–1.919 | < 0.001 |
| LNR (categorical variable) | 1.376 | 1.082–1.750 | < 0.001 | 1.287 | 1.056–1.569 | 0.012 |
| Number of RLNs (continuous variable) | 0.992 | 0.983–1.000 | 0.057 | 0.990 | 0.0.983–0.997 | 0.004 |
| Number of positive lymph nodes (continuous variable) | 1.073 | 1.033–1.114 | < 0.001 | 1.071 | 1.399–1.866 | < 0.001 |
| RT | 0.765 | 0.619–0.945 | 0.013 | 0.729 | 0.614–0.865 | < 0.001 |
Abbreviations: CCSS, cervical cancer-related survival; OS, overall survival; HR, hazard ratio; CI, confidence interval; RT, radiotherapy; FIGO, International Federation of Gynecology and Obstetrics; LNR, lymph node ratio; RLNs, removed lymph nodes.