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. 2016 Apr 15;7(20):29429–29439. doi: 10.18632/oncotarget.8738

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Copyright: © 2016 Wei et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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A. PNN in 8 CRC cell lines analyzed by Western blot. B and C. Down-regulation of PNN inhibited proliferation of SW620 determined by CCK-8 and colony formation assays. D and E. Down-regulation of PNN inhibited migration and invasion of SW620 determined by transwell assays. F. and G. Ectopic expression of PNN stimulated proliferation of SW480 determined by CCK-8 and colony formation assays. H and I. Ectopic expression of PNN promoted migration and invasion of SW480 determined by transwell assays. Error bars represent mean±SD.