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. 2016 Apr 15;7(20):29429–29439. doi: 10.18632/oncotarget.8738

Figure 5. DSG2 and ERK inhibitor reverses the effect of PNN on proliferation and migration in vitro.

Figure 5

A. Indicated proteins of SW480/Vector and SW480/PNN, SW620/N.C and SW620/Si-PNN analyzed by Western blot. B and C. PNN and DSG2 of SW480/Vector and SW480/PNN, SW620/N.C and SW620/Si-PNN analyzed by IFC. D. Indicated proteins of SW480/Vector and SW480/PNN combined with treatment of Si-DSG2 analyzed by Western blot. E and F. Combined effect of PNN and DSG2 on SW480 proliferationdetermined by CCK-8 and colony formation assays. G. Combined effect of PNN and DSG2 on SW480 migration determined by transwell assays. H. Indicated proteins of SW480/Vector and SW480/PNN combined with ERK blocker. I and J. Effect of ERK blocker on proliferation of SW480/Vector and SW480/PNN determined by CCK-8 and colony formation assays. K. Effect of ERK blocker on migration of SW480/Vector and SW480/PNN determined by transwell assays. Error bars represent mean±SD.