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Increased glucose tolerance but normal insulin sensitivity in FKBP51-KO mice fed a HF diet. A, WT (n = 6) and KO (n = 5) 5-month-old mice fed a RD were fasted overnight (GTT) or 6 hours (ITT), followed by measurement of glucose tolerance (GTT) or insulin sensitivity (ITT), respectively. B, GTT and ITT assays performed on WT (n = 7) and KO (n = 8) 5-month-old mice at the end of a 4-week HF diet. Data shown are mean ± SEM. *, WT vs KO.
