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Macrophage VDR expression is required for the inflammatory response to tissue injury. A, IHC analyses for F4/80 were performed on 2-day wounds of WT, VDR KO, and Lys-Cre VDR f/f mice. B, Graphs represent the number of F4/80-positive cells per high-power field. Data are based on five to six wounds per genotype. *, P < .0001 vs WT by ANOVA (VDR KO vs VDRf/f,Lys-Cre, P = NS). DAPI, 4′,6′-diamino-2-phenylindole.
