Skip to main content
PMC home page
The British Journal of Ophthalmology logoLink to The British Journal of Ophthalmology
. 1993 Jul;77(7):417–423. doi: 10.1136/bjo.77.7.417

A population based, prospective study of the development of ROP in prematurely born children in the Stockholm area of Sweden.

G Holmström 1, M el Azazi 1, L Jacobson 1, G Lennerstrand 1
PMCID: PMC504552  PMID: 8343469

Abstract

A prospective population based study including 260 children with a birth weight of 1500 g or less was performed in the Stockholm county. The total incidence of retinopathy of prematurity (ROP) was 40.4%, while severe ROP--that is, stage 3 or more, was seen in 20.0%. Cryotherapy was performed in 10.8%. Logistic regression analysis revealed independent association of both gestational age and birth weight with ROP. The association of gestational age and ROP was significantly stronger, indicating that the degree of immaturity of the eye is a main predictive factor for the development of ROP. The purpose of a general screening for ROP is to identify children requiring cryotherapy. Based on these results it seems appropriate to include children with a gestational age of 32 weeks or less in such a programme and a first examination at 5-6 weeks of postnatal age is suggested.

Full text

PDF
417

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Acheson J. F., Schulenburg W. E. Surveillance for retinopathy of prematurity in practice: experience from one neonatal intensive care unit. Eye (Lond) 1991;5(Pt 1):80–85. doi: 10.1038/eye.1991.16. [DOI] [PubMed] [Google Scholar]
  2. Brown D. R., Biglan A. W., Stretavsky M. A. Screening criteria for the detection of retinopathy of prematurity in patients in a neonatal intensive care unit. J Pediatr Ophthalmol Strabismus. 1987 Sep-Oct;24(5):212–215. doi: 10.3928/0191-3913-19870901-03. [DOI] [PubMed] [Google Scholar]
  3. Darlow B. A. Incidence of retinopathy of prematurity in New Zealand. Arch Dis Child. 1988 Sep;63(9):1083–1086. doi: 10.1136/adc.63.9.1083. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Fielder A. R., Levene M. I. Screening for retinopathy of prematurity. Arch Dis Child. 1992 Jul;67(7 Spec No):860–867. doi: 10.1136/adc.67.7_spec_no.860. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Fielder A. R., Ng Y. K., Levene M. I. Retinopathy of prematurity: age at onset. Arch Dis Child. 1986 Aug;61(8):774–778. doi: 10.1136/adc.61.8.774. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Fielder A. R., Shaw D. E., Robinson J., Ng Y. K. Natural history of retinopathy of prematurity: a prospective study. Eye (Lond) 1992;6(Pt 3):233–242. doi: 10.1038/eye.1992.46. [DOI] [PubMed] [Google Scholar]
  7. Fledelius H. C. Retinopathy of prematurity. Clinical findings in a Danish County 1982-87. Acta Ophthalmol (Copenh) 1990 Apr;68(2):209–213. doi: 10.1111/j.1755-3768.1990.tb01906.x. [DOI] [PubMed] [Google Scholar]
  8. Fledelius H. C., Rosenberg T. Retinopathy of prematurity. Where to set screening limits? Recommendations based on two Danish surveys. Acta Paediatr Scand. 1990 Oct;79(10):906–910. doi: 10.1111/j.1651-2227.1990.tb11351.x. [DOI] [PubMed] [Google Scholar]
  9. Flynn J. T., Bancalari E., Bachynski B. N., Buckley E. B., Bawol R., Goldberg R., Cassady J., Schiffman J., Feuer W., Gillings D. Retinopathy of prematurity. Diagnosis, severity, and natural history. Ophthalmology. 1987 Jun;94(6):620–629. [PubMed] [Google Scholar]
  10. Gallo J. E., Holmström G., Kugelberg U., Hedquist B., Lennerstrand G. Regressed retinopathy of prematurity and its sequelae in children aged 5-10 years. Br J Ophthalmol. 1991 Sep;75(9):527–531. doi: 10.1136/bjo.75.9.527. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Gallo J. E., Lennerstrand G. A population-based study of ocular abnormalities in premature children aged 5 to 10 years. Am J Ophthalmol. 1991 May 15;111(5):539–547. doi: 10.1016/s0002-9394(14)73695-5. [DOI] [PubMed] [Google Scholar]
  12. Johnson L. H., Quinn G. E., Abbasi S., Bowen F. W. Retinopathy of prematurity: prevalence and treatment over a 20 year period at Pennsylvania Hospital. Doc Ophthalmol. 1990 Mar;74(3):213–222. doi: 10.1007/BF02482611. [DOI] [PubMed] [Google Scholar]
  13. Kalina R. E., Karr D. J. Retrolental fibroplasia. Experience over two decades in one institution. Ophthalmology. 1982 Feb;89(2):91-5, 103. doi: 10.1016/s0161-6420(82)34829-0. [DOI] [PubMed] [Google Scholar]
  14. Keith C. G., Kitchen W. H. Ocular morbidity in infants of very low birth weight. Br J Ophthalmol. 1983 May;67(5):302–305. doi: 10.1136/bjo.67.5.302. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Kingham J. D. Acute retrolental fibroplasia. Arch Ophthalmol. 1977 Jan;95(1):39–47. doi: 10.1001/archopht.1977.04450010041003. [DOI] [PubMed] [Google Scholar]
  16. Ng Y. K., Fielder A. R., Shaw D. E., Levene M. I. Epidemiology of retinopathy of prematurity. Lancet. 1988 Nov 26;2(8622):1235–1238. doi: 10.1016/s0140-6736(88)90820-3. [DOI] [PubMed] [Google Scholar]
  17. Nissenkorn I., Axer-Siegel R., Kremer I., Ben-Sira I. Effect of partial cryoablation on retinopathy of prematurity. Br J Ophthalmol. 1991 Mar;75(3):160–162. doi: 10.1136/bjo.75.3.160. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Nissenkorn I., Ben Sira I., Kremer I., Gaton D. D., Krikler R., Wielunsky E., Merlob P. Eleven years' experience with retinopathy of prematurity: visual results and contribution of cryoablation. Br J Ophthalmol. 1991 Mar;75(3):158–159. doi: 10.1136/bjo.75.3.158. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Nissenkorn I., Kremer I., Gilad E., Cohen S., Ben-Sira I. 'Rush' type retinopathy of prematurity: report of three cases. Br J Ophthalmol. 1987 Jul;71(7):559–562. doi: 10.1136/bjo.71.7.559. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Palmer E. A., Flynn J. T., Hardy R. J., Phelps D. L., Phillips C. L., Schaffer D. B., Tung B. Incidence and early course of retinopathy of prematurity. The Cryotherapy for Retinopathy of Prematurity Cooperative Group. Ophthalmology. 1991 Nov;98(11):1628–1640. doi: 10.1016/s0161-6420(91)32074-8. [DOI] [PubMed] [Google Scholar]
  21. Palmer E. A. Optimal timing of examination for acute retrolental fibroplasia. Ophthalmology. 1981 Jul;88(7):662–668. doi: 10.1016/s0161-6420(81)34980-x. [DOI] [PubMed] [Google Scholar]
  22. Phelps D. L., Brown D. R., Tung B., Cassady G., McClead R. E., Purohit D. M., Palmer E. A. 28-day survival rates of 6676 neonates with birth weights of 1250 grams or less. Pediatrics. 1991 Jan;87(1):7–17. [PubMed] [Google Scholar]
  23. Phelps D. L. Retinopathy of prematurity: an estimate of vision loss in the United States--1979. Pediatrics. 1981 Jun;67(6):924–925. [PubMed] [Google Scholar]
  24. Quinn G. E., Johnson L., Abbasi S. Onset of retinopathy of prematurity as related to postnatal and postconceptional age. Br J Ophthalmol. 1992 May;76(5):284–288. doi: 10.1136/bjo.76.5.284. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Reisner S. H., Amir J., Shohat M., Krikler R., Nissenkorn I., Ben-Sira I. Retinopathy of prematurity: incidence and treatment. Arch Dis Child. 1985 Aug;60(8):698–701. doi: 10.1136/adc.60.8.698. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. SILVERMAN W. A., BLODI F. C., LOCKE J. C., DAY R. L., REESE A. B. Incidence of retrolental fibroplasia in a New York nursery. AMA Arch Ophthalmol. 1952 Dec;48(6):698–711. doi: 10.1001/archopht.1952.00920010710005. [DOI] [PubMed] [Google Scholar]
  27. Saigal S., Rosenbaum P., Stoskopf B., Milner R. Follow-up of infants 501 to 1,500 gm birth weight delivered to residents of a geographically defined region with perinatal intensive care facilities. J Pediatr. 1982 Apr;100(4):606–613. doi: 10.1016/s0022-3476(82)80767-1. [DOI] [PubMed] [Google Scholar]
  28. Schulenburg W. E., Prendiville A., Ohri R. Natural history of retinopathy of prematurity. Br J Ophthalmol. 1987 Nov;71(11):837–843. doi: 10.1136/bjo.71.11.837. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. Tan K. E., Cats B. P. Timely incidence of retinopathy of prematurity and its consequences for the screening strategy. Am J Perinatol. 1989 Jul;6(3):337–340. doi: 10.1055/s-2007-999609. [DOI] [PubMed] [Google Scholar]
  30. Tasman W. The natural history of active retinopathy of prematurity. Ophthalmology. 1984 Dec;91(12):1499–1503. doi: 10.1016/s0161-6420(84)34120-3. [DOI] [PubMed] [Google Scholar]

Articles from The British Journal of Ophthalmology are provided here courtesy of BMJ Publishing Group

RESOURCES