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Autoradiograms of tumors after dosing with [3H]BMS-753493. The representative autoradiograms of tumor following i.v. doses (2.2 nmol/kg or 4 mg/kg) of [3H]BMS-753493 to tumor-bearing mice at 24 and 48 h. The sections were to compare radioactivity distribution in M109 (FR–) and 98M109 (FR+) tumors. Details of whole-body autoradiography are described in the Section of Materials and methods.
