Figure 1.

Expression of drug processing genes (DPGs) in small and large intestine of mice. The mRNA abundance of DPGs was retrieved from BioGPS (Biogps.org, Su et al.²⁶). The abundance of DPGs was expressed as average probe intensity from the microarray data in BioGPS. DPGs that were highly expressed in at least one section of intestine and/or are known as CAR-target genes (Aleksunes and Klaassen²⁴) in liver were selected for the analysis (n=2 per tissue). For each graph, black bar represents DPG expression in the small intestine whereas red bar represents DPG expression in the large intestine.