Fig. 1.

Summary of PSME1 immunohistochemistry results. Variable expression of PSME1 both in the cytoplasm (a) as well as in the nucleus (b) in soft tissue sarcomas, while expression in uterine leiomyoma (LM; control) is low. LMS leiomyosarcomas, LPS pleomorphic liposarcomas, MFS myxofibrosarcomas, RMS pleomorphic rhabdomyosarcomas, UPS undifferentiated pleomorphic sarcomas, and USCS undifferentiated spindle cell sarcomas. In leiomyosarcomas, both cytoplasmic (c) and nuclear (d) expression increased with increasing histological grade (p = 0.00045 and p = 0.000357). In addition, both cytoplasmic and nuclear expression of PSME1 was significantly higher in intermediate and high grade leiomyosarcomas as compared to uterine leiomyomas (p ≤ 0.05/p ≤ 0.01). All score data for each group were presented in mean ± SD