Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A cationic nanogel developed for intranasal delivery of a subunit botulism neurotoxin. (A) The nanogel was self-assembled by the polysaccharide pullulan modified with cholesteryl and amino groups. Intranasal immunization with antigen-loaded nanogels significantly enhanced nasal residence of the antigen (B), antigen-specific antibody titers (C), and protection against challenge with the neurotoxin (D), compared with the soluble antigen. Reproduced with permission from ref. 72.
