Table 3.
Characteristics and survival in 12 low-grade MPNSTs
| Subtype | Age | Location | Neurofibroma component |
Depth | Therapy | Surgical Margins |
LR | DR | DOD |
|---|---|---|---|---|---|---|---|---|---|
| NF1 | 26 | Thoracic spine | Spinal | D | None | R0 | − | − | − |
| NF1 | 39 | Intercostal nerve | Plexiform | D | None | R0 | − | − | − |
| NF1 | 47 | Sciatic nerve, thigh | Diffuse | D | None | R0 | − | − | − |
| NF1 | 43 | Brachial plexus | Plexiform | D | None | R1 | − | − | − |
| NF1 | 69 | Back | Plexiform | S | RT | R1 | − | − | − |
| RAS | 60 | Brachial plexus | None | D | None | R2 | + | − | − |
| Sporadic | 68 | Chest | None | S | RT | R0 | − | − | − |
| Sporadic | 13 | Forehead | None | S | None | R1 | + | − | − |
| Sporadic | 60 | Lumbosacral | None | D | CT | R0 | + | − | − |
| Sporadic | 40 | Peritoneum | None | D | None | R0 | − | − | − |
| Sporadic | 64 | Shoulder | None | S | None | R0 | − | − | − |
| Sporadic | 79 | Retroperitoneum | None | D | CT | R0 | − | − | − |
Abbreviations: CT, chemotherapy; D, deep; DOD, MPNST-specific death; DR, distant recurrence; LR, local recurrence; RAS, radiation-associated; RT, radiation therapy; S, superficial