Table 7.
Authors & Year | No. Patients |
5 year survival |
Adverse prognostic features | Therapy Benefit |
|||||
---|---|---|---|---|---|---|---|---|---|
NF1 | RAS | Location | Size | Positive Margins |
RT | CT | |||
Present series | 289 | 52%a | T | NS | T (trunk) | S (≥ 10 cm) | S | NS | NS |
LaFemina et al., 2013 | 105 | - | NS | S | NS | S (larger) | S | - | - |
Fan et al., 2013 | 146 | 57% b | NS | - | NS | NS | NS | NS | NS |
Stucky et al., 2011 | 175 | 60% a | T | - | S (trunk) | S (≥ 5cm) | NS | NS | NS |
Zou et al., 2009 | 140 | 39% a | NS | NS | NS | S (≥ 10 cm) | NS | NS | NS |
Porter et al., 2008 | 123 | 51% b | S | - | NS | S (> 200 ml) | NS | NS | NS |
Anghileri et al., 2006 | 205 | 40% a | NS | - | S (trunk, HN) | S (larger) | S | S | NS |
Abbreviations: CT, chemotherapy; HN, head/neck; NF1, neurofibromatosis type1-associated MPNST; NS, not statistically significant; RAS, radiation-associated MPNST; RT, radiation therapy ; S, statistically significant; T, trend
Disease-specific survival
Overall survival
Tri-site series for a single-institution