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. Author manuscript; available in PMC: 2017 Oct 25.
Published in final edited form as: Chem Biol Interact. 2016 Aug 16;258:21–29. doi: 10.1016/j.cbi.2016.08.010

FIGURE 2.

FIGURE 2

Effect of epigenetic inhibitors on docetaxel-induced cytotoxicity in LNCaP cells. Cells were pretreated with 5-Aza or TSA for 30 min prior to 48 hr exposure to docetaxel and cytotoxicity was measured via changes in MTT staining (A, B) and phase contrast microscopy (C-F). Data in A and B are indicative of results from at least 6 separate passages per cell line (n ≥ 6) and are expressed as mean ± SD. (* p < 0.05 compared to control, # p < 0.05 compared to respective docetaxel treatment alone by One-way ANOVA followed by Bonferonni post-hoc test)