Table 11. The genes targeted by the 30 potential drugs.

NPC1 (20) U	IL1B (14) U	PPP3CA (10) U	HSPA1A (4) U	PTBP1 (3) U
CYP51A1 (2) U	RNASEH1 (1) U	CDK19 (1) U	AKT3 (1) U	INSR (1) U
TP53 (23) D	ADRB2 (23) D	RGS4 (22) D	SMPD1 (17) D	POLI (17) D
BAZ2B (15) D	MMP14 (15) D	BCL2L1 (15) D	NR2F2 (14) D	SUMO1 (14) D
VIPR1 (10) D	EGFR (10) D	ID4 (9) D	RXRA (7) D	PLEC (5) D
NLRP1 (5) D	STAT1 (4) D	WEE1 (4) D	STK3 (3) D	SRPK1 (3) D
SGK1 (3) D	MKNK2 (3) D	DUSP1 (2) D	PLAU (1) D	CDC42BPA (1) D
CDK2 (1) D	KDR (1) D	SIK1 (1) D

Note:

The parentheses represent the number of associated cMap drugs, U and D represent up and down-regulated respectively.