Table 12. The MTT and clonogenic assay values (IC50), target gene (DEG) and ICdb50 information for the cMAP drugs.
| Drug name | MTT/Clonogenic IC50 (μM) | DEG | ICdb50 (μM) | Study* |
|---|---|---|---|---|
| Lomustine | −/< 10 | SUMO1 | – | – |
| Parthenolide | > 5/− | TP53 | 15.5 | Kurdi & Booz (2007) and Weng et al. (2009) |
| Phenoxybenzamine | > 5/− | SUMO1 | – | Corvera et al. (2003) and Kulik et al. (2007) |
| Piperlongumine | > 5/− | TP53 | 3.16 | Son et al. (2012) |
| SUMO1 | – | |||
| Securinine | > 5/− | TP53 | 29.8 | – |
| Sulconazole | −/< 10 | SUMO1 | – | – |
| Tanespimycin | < 1/− | SUMO1 | – | Kim et al. (2014) |
| Thiostrepton | < 5/− | TP53 | 7.38 | – |
| Trifluoperazine | < 10/− | TP53 | 19.95 | Hong et al. (2014) |
| SUMO1 | – | |||
| Vorinostat | < 1/− | TP53 | 0.708 | Zhao et al. (2012) |
| SUMO1 | – |
Note:
*
Denotes studies shown evidence related to CVDs.
‘-’ denotes not determined.