Table 1.
Participant demographics and cognitive characteristics
| Study group | aMCI (n = 17) | Matched controls (n = 17) | P value |
|---|---|---|---|
| Variables | |||
| Female | 13 | 13 | — |
| Age | |||
| 60–70 | 5 | 5 | — |
| 71–80 | 7 | 7 | — |
| 81–90 | 5 | 5 | — |
| Average | 74 | 74 | — |
| Race | |||
| African American | 5 | 5 | — |
| Caucasian | 12 | 12 | — |
| Hypertension∗ | 7/17 | 8/17 | — |
| Diabetes∗ | 6/17 | 3/17 | — |
| Average RAVLT (total = 15) | 5.0 ± 3.91 | 11.1 ± 2.87 | <.001 |
| Average LMI (total = 25) | 8.7 ± 3.12 | 16.3 ± 3.35 | <.001 |
| Average LMII (total = 25) | 7.3 ± 4.55 | 16.35 ± 4.50 | <.001 |
| Average TMT-B† | 106.6 ± 224.67 | 80.3 ± 34.95 | .07 |
| Average MMSE (total = 30) | 27 ± 3.72 | 29 ± 0.70 | .03 |
Abbreviations: aMCI, amnestic mild cognitive impairment; RAVLT, Rey Auditory Verbal Learning Test; LMI, logical memory test I or immediate recall; LMII, logical memory test II or delayed recall; TMT-B, Trail Making Test, part B; MMSE, Mini-Mental State Examination.
∗
Subjects with retinopathy related to hypertension or diabetes were excluded.
†
TMT-B scores generally fell within normal limits for the age group studied.