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JMJD2A overexpression increased the levels of ANP and BNP. Cardiac cells were transfected at a ratio of 1 : 4 DNA : Lipofectamine, treated with Ang II 200 mM and ET-1. The results were calculated according to changes in the ANP and BNP levels after the transfection compared with the empty expression vector, which was used as a control. Data are from three independent experiments. ∗ p < 0.05 ∗∗ p < 0.01.
