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. 2016 Oct 3;6:34172. doi: 10.1038/srep34172

Table 1. Top10 proteins by degree in CePPIN.

Symbol Name Degree Betweenness centrality
APP Amyloid precursor protein 1960 0.2206
HNF4A Hepatocyte nuclear factor 4, alpha 1761 0.1858
ELAVL1 ELAV like RNA binding protein 1 1732 0.1931
ESR1 Estrogen receptor 1 799 0.0434
MYC v-myc avian myelocytomatosis viral oncogene homolog 714 0.0441
FN1 Fibronectin 1 689 0.0323
TP53 Tumor protein p53 661 0.0446
SIRT7 Sirtuin 7 655 0.0350
CAND1 Cullin-associated and neddylation-dissociated 1 619 0.0269
YWHAZ Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 616 0.0329