Table 2. Correlation between hepcidin and all variables in the HBV-related patients.
| Parameters | Chronic hepatitis B | HBV-related cirrhosis | HBV-related cirrhosis with HCC | Total patients | r | p-value | r | p-value |
|---|---|---|---|---|---|---|---|---|
| r | p-value | r | p-value | |||||
| AST (U/L) | 0.03 | — | −0.19 | — | 0.11 | — | 0.05 | — |
| ALT (U/L) | 0.07 | — | 0.44 | — | 0.12 | — | 0.05 | — |
| ALP (U/L) | −0.13 | — | −0.2 | — | 0.08 | — | 0.06 | — |
| TBIL (μmol/L) | −0.18 | — | −0.17 | — | −0.09 | — | 0.07 | — |
| Albumin (g/L) | 0.08 | — | −0.49 | — | 0.33 | — | 0.32 | <0.05 |
| Hemoglobin (g/L) | 0.16 | — | −0.10 | — | 0.11 | — | 0.26 | — |
| HBV-DNA (IU/mL) | 0.76 | <0.01 | 0.60 | <0.05 | 0.55 | — | 0.48 | <0.01 |
| Serum iron (μmol/L) | 0.33 | — | 0.40 | — | −0.06 | — | 0.13 | — |
| TIBC (μmol/L) | −0.06 | — | −0.51 | — | 0.21 | — | −0.11 | — |
| Ferritin (ng/mL) | 0.41 | — | 0.56 | <0.05 | 0.79 | <0.01 | 0.62 | <0.001 |
| CRP (ng/mL) | −0.28 | — | −0.46 | — | 0.14 | — | −0.06 | — |
Pearson’s or Spearman’s correlation analysis was performed for r and p values according to variable distribution. Abbreviations: HBV, hepatitis B virus; HCC, hepatocellular carcinoma; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALP, alkaline phosphatase; TBIL, total bilirubin; TIBC, iron and total iron-binding capacity; CRP, C-reactive protein.