Table 1. Animal study design, tests performed and number of animals (replicates) per test.

NaBu total dose (μg)	Test and Replicate Number
	Haemoglobin (Hb) N-acetyl-β-D-glucosaminidase (NAG) VEGF Analysis	Histology
0.1	8	5
0.5	8	5
1.0	8	5
5.0	8	5
10.0	8	5
50.0	8	5
100.0	8	5
0 (Control)	8	5
Total animals	64	40