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Breast cancer-specific survival probability according to ER status and the presence of a BRCA2 mutation in two time periods. (A) BRCA2 carriers diagnosed in 1935 through 1979. (B) BRCA2 carriers diagnosed in 1980 through 2012. (C) Non-carriers diagnosed in 1935 to 1979. (D) Non-carriers diagnosed in 1980 to 2012.
