Table 4. Multivariable logistic regression OR for colon and rectal cancer diagnosed after EP compared with non-EP taking into account patient socio-demographic characteristics, number of GP consultations for any reason the year before diagnosis (excluding 30 days) and symptoms recorded in primary care (N=1606).
Colon Cancer |
Rectal Cancer |
|||||||
---|---|---|---|---|---|---|---|---|
OR | 95% CI | P-value | OR | 95% CI | P-value | |||
Gender | ||||||||
Men | 1 | 1 | ||||||
Women | 1.37 | 1.04 | 1.82 | 0.028 | 1.49 | 0.89 | 2.48 | 0.128 |
Age (years) | ||||||||
25–59 | 1.09 | 0.68 | 1.74 | 0.721 | 0.47 | 0.16 | 1.34 | 0.158 |
60–69 | 1 | 1 | ||||||
70–79 | 1.02 | 0.69 | 1.53 | 0.910 | 0.79 | 0.41 | 1.53 | 0.491 |
80+ | 1.84 | 1.24 | 2.73 | 0.002 | 1.40 | 0.75 | 2.62 | 0.286 |
Socio-economic deprivation quintile | ||||||||
1 (least deprived) | 1 | 1 | ||||||
2 | 1.29 | 0.84 | 2.00 | 0.247 | 1.48 | 0.67 | 3.28 | 0.333 |
3 | 0.88 | 0.61 | 1.28 | 0.513 | 1.44 | 0.68 | 3.06 | 0.344 |
4 | 1.11 | 0.76 | 1.62 | 0.584 | 2.30 | 1.00 | 5.26 | 0.049 |
5 (most deprived) | 1.50 | 0.92 | 2.45 | 0.106 | 3.47 | 1.50 | 8.03 | 0.004 |
No. of GP visits between 30 days and 12 months pre-diagnosis | 1.00 | 0.99 | 1.01 | 0.658 | 1.03 | 1.01 | 1.06 | 0.008 |
Symptoms recorded between 30 days and 12 months pre-diagnosis | ||||||||
Anaemia | 0.38 | 0.26 | 0.55 | <0.001 | 0.73 | 0.28 | 1.92 | 0.530 |
Change in bowel habits | 0.47 | 0.25 | 0.87 | 0.017 | 0.60 | 0.26 | 1.41 | 0.241 |
Rectal bleeding | 0.22 | 0.12 | 0.41 | <0.001 | 0.25 | 0.11 | 0.58 | 0.001 |
Symptoms recorded between 25–60 months pre-diagnosis | ||||||||
Anaemia | 1.68 | 0.75 | 3.77 | 0.212 | 2.67 | 0.80 | 8.86 | 0.109 |
Change in bowel habits | 0.73 | 0.21 | 2.50 | 0.617 | 11.96 | 1.55 | 92.09 | 0.017 |
Rectal bleeding | 0.46 | 0.19 | 1.11 | 0.085 | 0.83 | 0.30 | 2.30 | 0.720 |
Abbreviations: CI=confidence interval; EP=emergency presentation; GP=general practioner; non-EP=non-emergency presentation; OR=odds ratio.