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. 2016 Aug 23;115(7):858–861. doi: 10.1038/bjc.2016.260

Table 3. Physician–patient ECOG PS disagreement and risk of mortality stratified by age, cancer type and sex.

Stratification variable Physician ECOG score n Physician rates PS better than patient HR (95% CI)a Physician rates PS worse than patient HR (95% CI)
Age⩽60 years (n=707) 0 439 2.71 (1.29–3.67) NAb
  1 213 1.60 (0.93–2.76) 0.83 (0.56–1.22)
  2+ 55 0.96 (0.44–2.10) 0.66 (0.31–1.42)
Age>60 years (n=711) 0 317 1.57 (1.08–2.28) NAb
  1 287 0.88 (0.61–1.28) 0.83 (0.56–1.22)
  2+ 107 1.33 (0.76–2.33) 0.74 (0.45–1.20)
Non-aggressive cancer (n=864) 0 500 2.58 (1.75–3.78) NAb
  1 276 1.33 (0.84–2.12) 0.59 (0.37–0.93)
  2+ 88 2.02 (1.05–3.87)) 0.71 (0.41–1.23)
Aggressive cancer (n=554) 0 256 1.14 (0.71–1.83) NAb
  1 224 0.80 (0.54–1.19) 0.97 (0.61–1.62)
  2+ 74 0.80 (0.58–3.55) 0.82 (0.45–1.49)
Female sex (n=587) 0 325 1.32 (0.81–2.15) NAb
  1 202 1.35 (0.81–2.26) 0.83 (0.46–1.50)
  2+ 60 1.09 (0.56–2.13) 0.44 (0.21–0.92)
Male sex (n=831) 0 431 2.23 (1.52–3.28) NAb
  1 298 0.87 (0.59–1.30) 0.66 (0.44–0.99)
  2+ 102 1.23 (0.65–2.33) 0.98 (0.58–1.65)

Abbreviations: CI=confidence interval; ECOG=Eastern Cooperative Oncology Group; HR=hazard ratio; NA=not available; PS=performance status.

a

Hazard ratio and 95% CIs calculated by Cox-proportional hazards models; models adjusted for sex, age, physician-assigned PS and cancer type.

b

Models did not run due to an empty cell in this category.