Table 3. Physician–patient ECOG PS disagreement and risk of mortality stratified by age, cancer type and sex.
Stratification variable | Physician ECOG score | n | Physician rates PS better than patient HR (95% CI)a | Physician rates PS worse than patient HR (95% CI) |
---|---|---|---|---|
Age⩽60 years (n=707) | 0 | 439 | 2.71 (1.29–3.67) | NAb |
1 | 213 | 1.60 (0.93–2.76) | 0.83 (0.56–1.22) | |
2+ | 55 | 0.96 (0.44–2.10) | 0.66 (0.31–1.42) | |
Age>60 years (n=711) | 0 | 317 | 1.57 (1.08–2.28) | NAb |
1 | 287 | 0.88 (0.61–1.28) | 0.83 (0.56–1.22) | |
2+ | 107 | 1.33 (0.76–2.33) | 0.74 (0.45–1.20) | |
Non-aggressive cancer (n=864) | 0 | 500 | 2.58 (1.75–3.78) | NAb |
1 | 276 | 1.33 (0.84–2.12) | 0.59 (0.37–0.93) | |
2+ | 88 | 2.02 (1.05–3.87)) | 0.71 (0.41–1.23) | |
Aggressive cancer (n=554) | 0 | 256 | 1.14 (0.71–1.83) | NAb |
1 | 224 | 0.80 (0.54–1.19) | 0.97 (0.61–1.62) | |
2+ | 74 | 0.80 (0.58–3.55) | 0.82 (0.45–1.49) | |
Female sex (n=587) | 0 | 325 | 1.32 (0.81–2.15) | NAb |
1 | 202 | 1.35 (0.81–2.26) | 0.83 (0.46–1.50) | |
2+ | 60 | 1.09 (0.56–2.13) | 0.44 (0.21–0.92) | |
Male sex (n=831) | 0 | 431 | 2.23 (1.52–3.28) | NAb |
1 | 298 | 0.87 (0.59–1.30) | 0.66 (0.44–0.99) | |
2+ | 102 | 1.23 (0.65–2.33) | 0.98 (0.58–1.65) |
Abbreviations: CI=confidence interval; ECOG=Eastern Cooperative Oncology Group; HR=hazard ratio; NA=not available; PS=performance status.
Hazard ratio and 95% CIs calculated by Cox-proportional hazards models; models adjusted for sex, age, physician-assigned PS and cancer type.
Models did not run due to an empty cell in this category.