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. 2016 Sep 8;115(7):784–788. doi: 10.1038/bjc.2016.281

Table 2. Summary of treatment-related adverse events.

  Grades 1 and 2
Grade 3
Grade 4
  N % N % N %
Leukopenia 8 17.4 4 8.7 6 13.0
Neutropenia 6 13 7 15.2 8 17.4
Lymphopenia 19 41.3 12 26.1 1 2.2
Febrile neutropenia 6 13.0
Anaemia 34 74 4 8.7
Thrombocytopenia 4 8.7 3 6.5
Nausea 3 6.5
Vomiting 6 13 1 2.2
Diarrhoea 5 10.8 2 4.3
Mucositis 3 6.5
Constipation 2 4.4
Neurotoxicity 5 10.9
Skin toxicity 4 8.7
Allergy 1 2.2
Infection 7 15.2 3 6.5
Fever 10 21.8
Fatigue 22 47.8 2 4.3
Oedema 1 2.2
Transaminase elevation 6 13
Dyspnoea 18 39.1 1 2.2
Nephrotoxicity 3 6.5
Headache 2 4.4