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. Author manuscript; available in PMC: 2017 Aug 25.
Published in final edited form as: Cell. 2016 Aug 25;166(5):1269–1281.e19. doi: 10.1016/j.cell.2016.07.049

Figure 6. Coordinated clusters of ER binding relies distal chromatin interactions.

Figure 6

(A) The cumulative distribution of JUN binding sites that are either bound or unbound by ER (black and red lines, respectively) as a function of proximity to the nearest ERE motif encoded ER binding site. (B) The cumulative distribution FOXA1 binding sites that are either bound or unbound by ER (black and red lines, respectively) as a function of proximity to the nearest ERE motif encoded ER binding site. (C) Prevalence of distal chromatin interactions at ER binding sites co-bound by FOXA1 binned by the significance of the best scoring match to the ERE contained in the binding site. (D) Distal ER interactions as in panel C, for sites with no evidence of FOXA1 binding.