KEY RESOURCES TABLE
REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Anti-GR antibody, rabbit polyclonal	Santa Cruz Biotechnology	sc-1003
Sheep anti-rabbit antibody beads	Life Technologies	M-280
Chemicals, Peptides, and Recombinant Proteins
Dexamethasone	Sigma-Aldrich	D4902
Critical Commercial Assays
PrepX mRNA seq kit	Wafergen	400039
PrepX ILM 32i DNA Library	Wafergen	400044
Dual-Glo Luciferase Assay	Promega	E2940
Fugene HD	Promega	E2312
Oligo-dT Dynabeads	ThermoFisher Sci.	61005
Superscript III reverse transcriptase	ThermoFisher Sci.	18080044
Q5 DNA Polymerase	New England Biolabs	M0491L
Turbo DNase	ThermoFisher Sci.	AM2238
In-Fusion HD Cloning Plus	Clonetech	638911
Deposited Data
Raw and analyzed data	This study	GEO: GSE79432 and GSE77869
Experimental Models: Cell Lines
A549 cells	ATCC/Duke Cancer Center Cell Culture Facility	CCL-185
Experimental Models: Organisms/Strains
E.coli MegaX DH10B Electrocomp cells	ThermoFisher Sci.	C640003
Recombinant DNA
pGL4.24 Lucferase Vector	Promega	E8421
pRL-TK	Promega	E2241
pRL-SV40	Promega	E2231
pSTARR-seq_human	Addgene	Plasmid #71509
Sequence-Based Reagents
PCR primers: Luciferase assay validation sequences, See Table S3	This study (IDT)	N/A
Gene block sequences: Luciferase assay AP-1-GRE spacing expts. See Table S3	This study (IDT)	N/A
Gene block sequences: Luciferase assay AP-1-GRE combination expts. See Table S3	This study (IDT)	N/A
PCR primer sequences: Sequencing library prep. See Table S3	This study (IDT)	N/A
STARR-seq adapter primers	Arnold et al., 2013	N/A
Nextera STARR-seq adapter primers, See Table S3	This study (IDT)	N/A
Software and Algorithms
MACS	Zhang et al. 2008	http://liulab.dfci.harvard.edu/MACS/
PeakSplitter	Salmon-Divon et al. 2010	http://www.bioinformatics.org/peakanalyzer/
BEDTools	Quinlan 2014	http://code.google.com/p/bedtools/
Bowtie/Bowtie2	Langmead et al. 2009; Langmead and Salzberg 2012	http://bowtie-bio.sourceforge.net/
SAMtools	Li et al. 2009	http://samtools.sourceforge.net
GraphPad Prism	GraphPad Inc.	http://www.graphpad.com/scientific-software/prism/
DEseq2	Love et al. 2014	http://www.bioconductor.org/packages/release/bioc/html/DESeq2
R	R Development Core Team, 2016	https://www.r-project.org/
MEME Suite	Bailey and Gribskov 1998	http://meme-suite.org/
pROC	Robin et al. 2011	http://web.expasy.org/pROC/
uShuffle	Jiang et al. 2008	http://digital.cs.usu.edu/~mjiang/ushuffle/