Cumulative incidence of deep molecular response. (A) MR4.0: the 2-year estimated cumulative incidence of MR4.0 was 51% (95% CI, 42–60%), B) MR4.5: the 2-year estimated cumulative incidence of MR4.5 was 24% (95% CI, 16–31%). The cumulative probability of achieving a response was calculated under consideration of competing risks, defined as failure followed by treatment change, progression or death.